New Technology in IVF | New Reproductive Technology | IVF Junction
IVF Technology

New Technology in IVF & New Reproductive Technology

Technological advancement in healthcare and healthcare systems is advancing and ever-evolving. In the timeline of the sequential progression of science and medicine, IVF is considered to be significant for the fact that it has rekindled the hopes of many childless parents. Advanced IVF techniques include preimplantation genetic screening, intracytoplasmic sperm injection, laser-assisted hatching, and so on. Now, the new technology in IVF that has been added to the list includes technologies such as the i-womb technology, oocyte activation through cult-active, embryo vitrification, and DNA fragmentation index, which assists in enhancing the chances of a successful IVF.

Every stage of IVF involves well-designed. The procedure is the fertilization of the retrieved eggs and sperms done in a laboratory set-up. Once the fertilization is done, the embryo is allowed to develop in an incubated environment that mimic’s the conditions of a mother’s womb. The mature embryos are selected and implanted carefully into the uterus of the mother.

While the whole IVF procedure is performed in vitro (external set-up), maintenance of ideal conditions for the storage of the gametes and the development of quality embryos becomes crucial. The new techniques in IVF treatment overcome different challenges that hamper the quality of gametes, amount of fertilized eggs, storage of embryos, culturing environment, and successful implantation.

What is the New Technology in IVF

i-Womb Technique – Application based Modern Embryology Lab

The fertilization process and the initial development of the embryo are done in an embryology lab. Grounded on the principle of artificial womb (AW) technology, the embryo labs replace the physiology and functioning of the uterus with a womb-like nurturing environment for optimal embryo growth.

Ideal conditions required for embryo growth such as optimum level of CO2, O2, the right temperature, and the exact amount of humidity need to be maintained in the embryology labs. Even the slightest variation in these conditions needs the immediate attention of the embryology lab monitoring team. To overcome this hurdle, continuous monitoring systems (CMS) are used that update every minute change in the incubated environment in real-time. This new reproductive technology adopts sensors and chips integrated with software-based data monitoring and recording systems that not only eases the meticulous monitoring procedure but ensures quality care and treatment.

Cult-Active Medium – Activation of oocytes after fertilization

Cult-Active is a novel method that can counter issues like low fertilized egg cells (oocytes) which indicate immature eggs. Generally, after ICSI(intracytoplasmic sperm injection), the initial activation of the egg(oocyte) is initiated by a protein present in the sperm. This initiation increases the concentration of calcium in the oocyte promoting embryo development.

Failure of activation can arrest the development of the embryo. Placement of the fertilized egg on the cult-active medium after ICSI for a short duration helps activate the oocyte and increase the amount of fertilized eggs. The calcium ionophore present in the cult-active medium connects the calcium ions to the eggs promoting a series of biochemical processes that activate the oocyte and embryo development.

Intracytoplasmic Sperm Injection (ICSI) – Precise fusion of the gametes

When the egg and the sperm are mixed in the laboratory and allowed to fuse, sometimes fertilization may not be optimal due to various reasons. ICSI is one such technique of IVF that can solve issues where the sperm is unable to make its way through the hard covering of the egg. Here, a tiny needle called a micropipette is used to inject the sperm into the egg’s center. After ICSI, the sperm is allowed to grow and later implanted.

Laser-Assisted Hatching – The controlled breaking of zona pellucida

The advent of lasers in IVF has paved the way for the development of accurate corrections and manipulation of embryos that is essential before their transfer. Laser-assisted hatching can improve the chances of optimal implantation and successful IVF.

The embryos have a protective outer shell called zona pellucida. Before the initiation of the transfer process, this outer shell layer must break up for precise implantation. Sometimes when the outer layer does not crack open, Infrared laser beams assist the removal of the protective layer enabling minimal handling and a quicker manipulation of embryos.

INVOcell – A capsuled embryo

A recent technology that can not only reduce the maintenance time of the embryo but also reduce the cost of the treatment. The egg and the sperm that is fused externally are placed in a capsule and inserted into the vagina for an incubation period of five days. After five days, the capsule is removed and the embryos formed within the capsule are implanted into the uterus. This technique utilizes the natural environment of the vagina for the initial embryo development offering a cost-effective alternative to the usual IVF procedure.

Preimplantation genetic screening/diagnosis (PGS/PGD) – Embryo screening

PGD/PGS are techniques that enable screening of the genetic elements within the embryo. A few cells of the embryo are screened for chromosomal anomalies like aneuploids, triploids, and the presence of any genetic defect like deletions, translocations of genes, etc. This elimination technique can help select embryos free from any genetic abnormality.

Egg/Embryo Vitrification – A cryopreservation technique

Cryopreservation is the freezing of the live cells, tissues using special servants called cryoprotectants. This freezing technique has been implemented in storing and preserving embryos. The embryos/eggs when frozen slowly, can involve the formation of ice crystals while freezing embryos. Thus damaging their DNA. To overcome this challenge, the egg/embryo vitrification process involves rapid freezing with the use of a new cryoprotectant that protects the egg/embryo from DNA damage and the formation of ice crystals. This technique allows women to preserve their fertility even if they want to delay their pregnancy.

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How IVF Junction helps you get the best treatment

While new technology in IVF has been adopted for the attainment of better outcomes, IVF junction makes every effort to bring you the best treatment. IVF technique is all about nurturing life and while nurturing, the safety, quality, and standardization of techniques is essential.

  • Our Standard embryology labs comply with quality treatment facilities like standardized procedures, proper equipment handling, and extensive infrastructure supporting continuous surveillance.
  • We understand your concern over the handling of gametes, embryos in our laboratories. We maintain transparency when it comes to securing your delicate future of a healthy progeny.
  • Our highly qualified team is working parallel to the emerging new reproductive technologies to make provisions for a more scientific, ethical, and effective approach and better result-oriented solutions for a successful IVF.
  • We follow a coding system for diagnostic sample collection as well as gamete and embryo collection which ensures no mistakes in the handling of samples and easy tracking in case of any failures.
  • IVF is a multi-staged procedure that requires adequate monitoring and precision. Our clinics are committed to providing you holistic care and treatment for the attainment of a smoother pregnancy.

IVF Junction connects you to the best IVF clinics in Delhi, NCR, and Gurgaon.

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